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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50249624   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM50249624
PNG
(CHEMBL4095178)
Show SMILES COc1cccnc1Cn1ccc2nc(N)nc(NCc3cc(C)on3)c12
Show InChI InChI=1S/C18H19N7O2/c1-11-8-12(24-27-11)9-21-17-16-13(22-18(19)23-17)5-7-25(16)10-14-15(26-2)4-3-6-20-14/h3-8H,9-10H2,1-2H3,(H3,19,21,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 6n/an/an/an/a



Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium.

Curated by ChEMBL


Assay Description
Agonist activity at TLR7 in human PBMC assessed as induction of IFNalpha-mediated inhibition of HCV genotype 1b RNA replication in human HuH luc/neo ...

J Med Chem 60: 6137-6151 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00365
BindingDB Entry DOI: 10.7270/Q2XP77CC
More data for this
Ligand-Target Pair