Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 50249669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50249669 (6-[(2-Furylmethyl)amino]-2,10-dihydroxy-13-(beta-D...) Show SMILES OC[C@H]1O[C@@H](On2c3cc(O)ccc3c3c4C(=O)N(NCc5ccco5)C(=O)c4c4c5ccc(O)cc5[nH]c4c23)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C31H26N4O11/c36-11-19-26(39)27(40)28(41)31(45-19)46-35-18-9-13(38)4-6-16(18)21-23-22(29(42)34(30(23)43)32-10-14-2-1-7-44-14)20-15-5-3-12(37)8-17(15)33-24(20)25(21)35/h1-9,19,26-28,31-33,36-41H,10-11H2/t19-,26-,27+,28-,31+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometer				J Med Chem 52: 3225-37 (2009) Article DOI: 10.1021/jm801641t BindingDB Entry DOI: 10.7270/Q23F4PJ0
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Mus musculus)	BDBM50249669 (6-[(2-Furylmethyl)amino]-2,10-dihydroxy-13-(beta-D...) Show SMILES OC[C@H]1O[C@@H](On2c3cc(O)ccc3c3c4C(=O)N(NCc5ccco5)C(=O)c4c4c5ccc(O)cc5[nH]c4c23)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C31H26N4O11/c36-11-19-26(39)27(40)28(41)31(45-19)46-35-18-9-13(38)4-6-16(18)21-23-22(29(42)34(30(23)43)32-10-14-2-1-7-44-14)20-15-5-3-12(37)8-17(15)33-24(20)25(21)35/h1-9,19,26-28,31-33,36-41H,10-11H2/t19-,26-,27+,28-,31+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS method				J Med Chem 52: 3225-37 (2009) Article DOI: 10.1021/jm801641t BindingDB Entry DOI: 10.7270/Q23F4PJ0
					More data for this Ligand-Target Pair