BindingDB PrimarySearch

Found 2 hits of ec50 for monomerid = 50249670
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50249670 (6-[(3-Furylmethyl)amino]-2,10-dihydroxy-13-(beta-D...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometer				J Med Chem 52: 3225-37 (2009) Article DOI: 10.1021/jm801641t BindingDB Entry DOI: 10.7270/Q23F4PJ0
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Mus musculus)	BDBM50249670 (6-[(3-Furylmethyl)amino]-2,10-dihydroxy-13-(beta-D...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	470	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by protinase K/SDS method				J Med Chem 52: 3225-37 (2009) Article DOI: 10.1021/jm801641t BindingDB Entry DOI: 10.7270/Q23F4PJ0
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair