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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 50263627   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))
BDBM50263627
PNG
(CHEMBL452423 | N-(2-((4-chlorophenyl)(phenyl)methy...)
Show SMILES Clc1ccc(cc1)C(NC(=O)CNC(=O)c1ccncc1)c1ccccc1
Show InChI InChI=1S/C21H18ClN3O2/c22-18-8-6-16(7-9-18)20(15-4-2-1-3-5-15)25-19(26)14-24-21(27)17-10-12-23-13-11-17/h1-13,20H,14H2,(H,24,27)(H,25,26)
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 200n/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human glycine transporter 1 transfected in Flp-inTM-CHO


Bioorg Med Chem Lett 18: 5533-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.005
BindingDB Entry DOI: 10.7270/Q2BR8S19
More data for this
Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))
BDBM50263627
PNG
(CHEMBL452423 | N-(2-((4-chlorophenyl)(phenyl)methy...)
Show SMILES Clc1ccc(cc1)C(NC(=O)CNC(=O)c1ccncc1)c1ccccc1
Show InChI InChI=1S/C21H18ClN3O2/c22-18-8-6-16(7-9-18)20(15-4-2-1-3-5-15)25-19(26)14-24-21(27)17-10-12-23-13-11-17/h1-13,20H,14H2,(H,24,27)(H,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human glycine transporter 2 transfected in Flp-inTM-CHO


Bioorg Med Chem Lett 18: 5533-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.005
BindingDB Entry DOI: 10.7270/Q2BR8S19
More data for this
Ligand-Target Pair