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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50272609   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50272609
PNG
(CHEMBL4127295)
Show SMILES Cl.Cl.C[C@@H](N[C@@H]1CCN(C1)c1ccc(cc1)C(O)=O)c1cccc2ccccc12 |r|
Show InChI InChI=1S/C23H24N2O2.2ClH/c1-16(21-8-4-6-17-5-2-3-7-22(17)21)24-19-13-14-25(15-19)20-11-9-18(10-12-20)23(26)27;;/h2-12,16,19,24H,13-15H2,1H3,(H,26,27);2*1H/t16-,19-;;/m1../s1
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n/an/an/an/a 8.80E+3n/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Agonist activity at human CaSR expressed in CHO cells assessed as increase in intracellular calcium mobilization after 1 hr by Fura-2 dye-based fluor...

Bioorg Med Chem Lett 28: 2055-2060 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.055
BindingDB Entry DOI: 10.7270/Q2DF6TP0
More data for this
Ligand-Target Pair