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Compile Data Set for Download or QSAR

Found 3 hits of ec50 for monomerid = 50292711   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trace amine-associated receptor 1


(Homo sapiens (Human))
BDBM50292711
PNG
(CHEMBL3628707)
Show SMILES NC(=N)NC(=N)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C12H18N6/c13-11(14)16-12(15)18-8-6-17(7-9-18)10-4-2-1-3-5-10/h1-5H,6-9H2,(H5,13,14,15,16)
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Article
PubMed
n/an/an/an/a 1.38E+3n/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay


Eur J Med Chem 146: 171-184 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.059
BindingDB Entry DOI: 10.7270/Q2445Q0T
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1


(Mus musculus (Mouse))
BDBM50292711
PNG
(CHEMBL3628707)
Show SMILES NC(=N)NC(=N)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C12H18N6/c13-11(14)16-12(15)18-8-6-17(7-9-18)10-4-2-1-3-5-10/h1-5H,6-9H2,(H5,13,14,15,16)
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Article
PubMed
n/an/an/an/a 2.38E+3n/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay


Eur J Med Chem 146: 171-184 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.059
BindingDB Entry DOI: 10.7270/Q2445Q0T
More data for this
Ligand-Target Pair
Trace amine-associated receptor 5


(Mus musculus)
BDBM50292711
PNG
(CHEMBL3628707)
Show SMILES NC(=N)NC(=N)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C12H18N6/c13-11(14)16-12(15)18-8-6-17(7-9-18)10-4-2-1-3-5-10/h1-5H,6-9H2,(H5,13,14,15,16)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay


Eur J Med Chem 146: 171-184 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.059
BindingDB Entry DOI: 10.7270/Q2445Q0T
More data for this
Ligand-Target Pair