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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50331987   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50331987
PNG
(2-(benzyloxy)-1-(4-(4-chloropyridin-2-yl)piperazin...)
Show SMILES Clc1ccnc(c1)N1CCN(CC1)C(=O)COCc1ccccc1
Show InChI InChI=1S/C18H20ClN3O2/c19-16-6-7-20-17(12-16)21-8-10-22(11-9-21)18(23)14-24-13-15-4-2-1-3-5-15/h1-7,12H,8-11,13-14H2
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Similars
Article
PubMed
n/an/an/an/a 570n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assay

Bioorg Med Chem Lett 20: 7381-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.10.036
BindingDB Entry DOI: 10.7270/Q27S7P13
More data for this
Ligand-Target Pair