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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50503515   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM50503515
PNG
(CHEMBL4560537 | US10626103, Example 83)
Show SMILES COc1ccc(cc1F)-n1c(C)c(nc1-c1ccc(C#N)c(F)c1)C(=O)N[C@H]1CCNC1 |r|
Show InChI InChI=1S/C23H21F2N5O2/c1-13-21(23(31)28-16-7-8-27-12-16)29-22(14-3-4-15(11-26)18(24)9-14)30(13)17-5-6-20(32-2)19(25)10-17/h3-6,9-10,16,27H,7-8,12H2,1-2H3,(H,28,31)/t16-/m0/s1
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n/an/an/an/a 160n/an/an/an/a



Celgene Corporation

Curated by ChEMBL


Assay Description
Inhibition of LSD1 in human THP1 cells assessed as induction of CD11b expression after 4 days by LIVE/DEAD violet staining based FACS analysis

Bioorg Med Chem Lett 29: 103-106 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.001
BindingDB Entry DOI: 10.7270/Q2W95DFG
More data for this
Ligand-Target Pair