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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50506230   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(MOUSE)		BDBM50506230
PNG
(CHEMBL4471389)
Show SMILES Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)c1cccc2cc[nH]c12)ccc3O |r,THB:11:10:18:7.6.5|
Show InChI InChI=1S/C29H31N3O4.ClH/c33-21-7-6-18-14-22-29(35)10-8-20(31-27(34)19-3-1-2-17-9-12-30-24(17)19)26-28(29,23(18)25(21)36-26)11-13-32(22)15-16-4-5-16;/h1-3,6-7,9,12,16,20,22,26,30,33,35H,4-5,8,10-11,13-15H2,(H,31,34);1H/t20-,22+,26-,28-,29+;/m0./s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.90n/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Agonist activity at recombinant mouse mu opioid receptor expressed in CHO cell membrane assessed as [35]-GTPgammaS binding incubated for 1.5 hrs by s...

J Med Chem 62: 11399-11415 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01767
BindingDB Entry DOI: 10.7270/Q2G73J1K
More data for this
Ligand-Target Pair