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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50514103   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50514103
PNG
(CHEMBL4579823)
Show SMILES OC(=O)\C=C\C(O)=O.CC(C)CNC1CN(C1)c1ccnc(N)n1
Show InChI InChI=1S/C11H19N5/c1-8(2)5-14-9-6-16(7-9)10-3-4-13-11(12)15-10/h3-4,8-9,14H,5-7H2,1-2H3,(H2,12,13,15)
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PC cid
PC sid
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Article
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n/an/an/an/a 5n/an/an/an/a



Vrije Universiteit Amsterdam

Curated by ChEMBL


Assay Description
Agonist activity at human H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...

J Med Chem 62: 10848-10866 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01462
BindingDB Entry DOI: 10.7270/Q2M61PKJ
More data for this
Ligand-Target Pair