Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50533232 (CHEMBL4564126) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 234 | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assay | Bioorg Med Chem Lett 26: 4334-9 (2016) Article DOI: 10.1016/j.bmcl.2016.07.030 BindingDB Entry DOI: 10.7270/Q2NV9NQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50533232 (CHEMBL4564126) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 234 | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assay | Bioorg Med Chem Lett 26: 4334-9 (2016) Article DOI: 10.1016/j.bmcl.2016.07.030 BindingDB Entry DOI: 10.7270/Q2NV9NQT | |||||||||||
More data for this Ligand-Target Pair |