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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50539246   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Palmitoleoyl-protein carboxylesterase NOTUM


(Homo sapiens (Human))		BDBM50539246
PNG
(CHEMBL4632439)
Show SMILES CN1CN(CC1=O)C(=O)CSc1ncnc2sc(c(C)c12)C(F)(F)F
Show InChI InChI=1S/C14H13F3N4O2S2/c1-7-10-12(18-5-19-13(10)25-11(7)14(15,16)17)24-4-9(23)21-3-8(22)20(2)6-21/h5H,3-4,6H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 210n/an/an/an/a



University College London

Curated by ChEMBL


Assay Description
Inhibition of NOTUM (unknown origin) transfected in human HEK293T cells harbouring TCF/LEF luciferase reporter gene assessed as activation of Wnt sig...

Bioorg Med Chem Lett 30: (2020)


Article DOI: 10.1016/j.bmcl.2019.126751
BindingDB Entry DOI: 10.7270/Q23X8B58
More data for this
Ligand-Target Pair