Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419177 (US10457678, Compound 33) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419183 (US10457678, Compound 36) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419140 (US10457678, Compound 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419178 (US10457678, Compound 34) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419153 (US10457678, Compound 26) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419173 (US10457678, Compound 32) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419141 (US10457678, Compound 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419182 (US10457678, Compound 35) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419159 (US10457678, Compound 21) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM419135 (US10457678, Compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a |
Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1 US Patent | Assay Description TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che... | US Patent US10457678 (2019) BindingDB Entry DOI: 10.7270/Q2S184V0 | |||||||||||
More data for this Ligand-Target Pair |