Compile Data Set for Download or QSAR

Found 27 hits of ec50 for UniProtKB: Q02294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295697 (2-(3-aminopropoxy)-N-(4-(3-(diaminomethyleneamino)...) Show SMILES [#7]-[#6]-[#6]-[#6]-[#8]-c1ccccc1-[#6](=O)-[#7](-[#6]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1)-c1nc2ccc(-[#8]-c3ccc(-[#8])cc3)cc2s1 Show InChI InChI=1S/C34H36N6O5S/c35-17-3-19-44-30-6-2-1-5-28(30)32(42)40(22-23-7-11-25(12-8-23)43-20-4-18-38-33(36)37)34-39-29-16-15-27(21-31(29)46-34)45-26-13-9-24(41)10-14-26/h1-2,5-16,21,41H,3-4,17-20,22,35H2,(H4,36,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295696 (2-(3-aminopropoxy)-N-(4-(3-(diaminomethyleneamino)...) Show SMILES [#7]-[#6]-[#6]-[#6]-[#8]-c1ccccc1-[#6](=O)-[#7](-[#6]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1)-c1nc2ccc(-[#8]-c3ccccc3)cc2s1 Show InChI InChI=1S/C34H36N6O4S/c35-18-6-20-43-30-11-5-4-10-28(30)32(41)40(23-24-12-14-25(15-13-24)42-21-7-19-38-33(36)37)34-39-29-17-16-27(22-31(29)45-34)44-26-8-2-1-3-9-26/h1-5,8-17,22H,6-7,18-21,23,35H2,(H4,36,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295695 (2-(3-aminopropoxy)-N-(4-(3-aminopropoxy)benzyl)-N-...) Show SMILES NCCCOc1ccc(CN(C(=O)c2ccccc2OCCCN)c2nc3ccc(Oc4ccc(O)cc4)cc3s2)cc1 Show InChI InChI=1S/C33H34N4O5S/c34-17-3-19-40-25-11-7-23(8-12-25)22-37(32(39)28-5-1-2-6-30(28)41-20-4-18-35)33-36-29-16-15-27(21-31(29)43-33)42-26-13-9-24(38)10-14-26/h1-2,5-16,21,38H,3-4,17-20,22,34-35H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295695 (2-(3-aminopropoxy)-N-(4-(3-aminopropoxy)benzyl)-N-...) Show SMILES NCCCOc1ccc(CN(C(=O)c2ccccc2OCCCN)c2nc3ccc(Oc4ccc(O)cc4)cc3s2)cc1 Show InChI InChI=1S/C33H34N4O5S/c34-17-3-19-40-25-11-7-23(8-12-25)22-37(32(39)28-5-1-2-6-30(28)41-20-4-18-35)33-36-29-16-15-27(21-31(29)43-33)42-26-13-9-24(38)10-14-26/h1-2,5-16,21,38H,3-4,17-20,22,34-35H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from rat brain membrane Cav2.2 after 1 hr by gamma counting method				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295697 (2-(3-aminopropoxy)-N-(4-(3-(diaminomethyleneamino)...) Show SMILES [#7]-[#6]-[#6]-[#6]-[#8]-c1ccccc1-[#6](=O)-[#7](-[#6]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1)-c1nc2ccc(-[#8]-c3ccc(-[#8])cc3)cc2s1 Show InChI InChI=1S/C34H36N6O5S/c35-17-3-19-44-30-6-2-1-5-28(30)32(42)40(22-23-7-11-25(12-8-23)43-20-4-18-38-33(36)37)34-39-29-16-15-27(21-31(29)46-34)45-26-13-9-24(41)10-14-26/h1-2,5-16,21,41H,3-4,17-20,22,35H2,(H4,36,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from rat brain membrane Cav2.2 after 1 hr by gamma counting method				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295701 (CHEMBL565078 | N-(3-{4-[(6-Phenoxy-benzothiazol-2-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#8]-c1ccc(-[#6]-[#7]-c2nc3ccc(-[#8]-c4ccccc4)cc3s2)cc1 Show InChI InChI=1S/C24H25N5O2S/c25-23(26)27-13-4-14-30-18-9-7-17(8-10-18)16-28-24-29-21-12-11-20(15-22(21)32-24)31-19-5-2-1-3-6-19/h1-3,5-12,15H,4,13-14,16H2,(H,28,29)(H4,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304189 (CHEMBL593380 | N-(4-(4-Fluorophenoxy)phenyl)-2-(8-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C32H41FN8O4/c33-22-8-12-24(13-9-22)45-25-14-10-23(11-15-25)40-30(43)27-21-26(44-20-6-19-39-32(36)37)16-17-28(27)41-29(42)7-4-2-1-3-5-18-38-31(34)35/h8-17,21H,1-7,18-20H2,(H,40,43)(H,41,42)(H4,34,35,38)(H4,36,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295707 (2-(3-(4-((2,2-diphenylethylamino)methyl)phenoxy)pr...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#8]-c1ccc(-[#6]-[#7]-[#6]-[#6](-c2ccccc2)-c2ccccc2)cc1 Show InChI InChI=1S/C25H30N4O/c26-25(27)29-16-7-17-30-23-14-12-20(13-15-23)18-28-19-24(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-6,8-15,24,28H,7,16-19H2,(H4,26,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304185 (2-(5-Guanidino-octanamido)-5-(3-guanidinopropoxy)-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccccc2)cc1 Show InChI InChI=1S/C32H42N8O4/c33-31(34)37-19-8-3-1-2-7-12-29(41)40-28-18-17-26(43-21-9-20-38-32(35)36)22-27(28)30(42)39-23-13-15-25(16-14-23)44-24-10-5-4-6-11-24/h4-6,10-11,13-18,22H,1-3,7-9,12,19-21H2,(H,39,42)(H,40,41)(H4,33,34,37)(H4,35,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304187 (2-(5-Guanidino-octanamido)-5-(3-guanidinobutoxy)-N...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccccc2)cc1 Show InChI InChI=1S/C33H44N8O4/c34-32(35)38-20-8-3-1-2-7-13-30(42)41-29-19-18-27(44-22-10-9-21-39-33(36)37)23-28(29)31(43)40-24-14-16-26(17-15-24)45-25-11-5-4-6-12-25/h4-6,11-12,14-19,23H,1-3,7-10,13,20-22H2,(H,40,43)(H,41,42)(H4,34,35,38)(H4,36,37,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304184 (2-(5-Guanidinohexanamido)-5-(3-guanidinopropoxy)-N...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccccc2)cc1 Show InChI InChI=1S/C30H38N8O4/c31-29(32)35-17-6-2-5-10-27(39)38-26-16-15-24(41-19-7-18-36-30(33)34)20-25(26)28(40)37-21-11-13-23(14-12-21)42-22-8-3-1-4-9-22/h1,3-4,8-9,11-16,20H,2,5-7,10,17-19H2,(H,37,40)(H,38,39)(H4,31,32,35)(H4,33,34,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304188 (2-(8-Guanidinooctanamido)-5-(3-guanidinopropoxy)-N...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccc(-[#8])cc2)cc1 Show InChI InChI=1S/C32H42N8O5/c33-31(34)37-18-5-3-1-2-4-7-29(42)40-28-17-16-26(44-20-6-19-38-32(35)36)21-27(28)30(43)39-22-8-12-24(13-9-22)45-25-14-10-23(41)11-15-25/h8-17,21,41H,1-7,18-20H2,(H,39,43)(H,40,42)(H4,33,34,37)(H4,35,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304186 (2-(5-Guanidinohexanamido)-5-(3-guanidinobutoxy)-N-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccccc2)cc1 Show InChI InChI=1S/C31H40N8O4/c32-30(33)36-18-6-2-5-11-28(40)39-27-17-16-25(42-20-8-7-19-37-31(34)35)21-26(27)29(41)38-22-12-14-24(15-13-22)43-23-9-3-1-4-10-23/h1,3-4,9-10,12-17,21H,2,5-8,11,18-20H2,(H,38,41)(H,39,40)(H4,32,33,36)(H4,34,35,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295703 (2-(3-(4-((4-phenoxyphenylamino)methyl)phenoxy)prop...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#8]-c1ccc(-[#6]-[#7]-c2ccc(-[#8]-c3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H26N4O2/c24-23(25)26-15-4-16-28-20-11-7-18(8-12-20)17-27-19-9-13-22(14-10-19)29-21-5-2-1-3-6-21/h1-3,5-14,27H,4,15-17H2,(H4,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295705 (2-(3-(4-((benzhydrylamino)methyl)phenoxy)propyl)gu...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#8]-c1ccc(-[#6]-[#7]-[#6](-c2ccccc2)-c2ccccc2)cc1 Show InChI InChI=1S/C24H28N4O/c25-24(26)27-16-7-17-29-22-14-12-19(13-15-22)18-28-23(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-6,8-15,23,28H,7,16-18H2,(H4,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295699 (2-(3-Guanidino-propoxy)-N-(6-phenoxy-benzothiazol-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#8]-c1ccccc1-[#6](=O)-[#7]-c1nc2ccc(-[#8]-c3ccccc3)cc2s1 Show InChI InChI=1S/C24H23N5O3S/c25-23(26)27-13-6-14-31-20-10-5-4-9-18(20)22(30)29-24-28-19-12-11-17(15-21(19)33-24)32-16-7-2-1-3-8-16/h1-5,7-12,15H,6,13-14H2,(H4,25,26,27)(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295702 (CHEMBL552193 | [4-(3-Amino-propoxy)-benzyl]-(4-phe...) Show SMILES NCCCOc1ccc(CNc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H24N2O2/c23-15-4-16-25-20-11-7-18(8-12-20)17-24-19-9-13-22(14-10-19)26-21-5-2-1-3-6-21/h1-3,5-14,24H,4,15-17,23H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304180 (2-(8-Aminooctanamido)-5-(3-aminopropoxy)-N-(4-phen...) Show SMILES NCCCCCCCC(=O)Nc1ccc(OCCCN)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C30H38N4O4/c31-19-8-3-1-2-7-12-29(35)34-28-18-17-26(37-21-9-20-32)22-27(28)30(36)33-23-13-15-25(16-14-23)38-24-10-5-4-6-11-24/h4-6,10-11,13-18,22H,1-3,7-9,12,19-21,31-32H2,(H,33,36)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295700 (CHEMBL550448 | [4-(3-Amino-propoxy)-benzyl]-(6-phe...) Show SMILES NCCCOc1ccc(CNc2nc3ccc(Oc4ccccc4)cc3s2)cc1 Show InChI InChI=1S/C23H23N3O2S/c24-13-4-14-27-18-9-7-17(8-10-18)16-25-23-26-21-12-11-20(15-22(21)29-23)28-19-5-2-1-3-6-19/h1-3,5-12,15H,4,13-14,16,24H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304190 (2-(5-Aminopentanamido)-5-(3-aminopropoxy)-N-(4-phe...) Show SMILES NCCCCC(=O)Nc1ccc(OCCCN)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H32N4O4/c28-16-5-4-9-26(32)31-25-15-14-23(34-18-6-17-29)19-24(25)27(33)30-20-10-12-22(13-11-20)35-21-7-2-1-3-8-21/h1-3,7-8,10-15,19H,4-6,9,16-18,28-29H2,(H,30,33)(H,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304182 (5-(4-Aminobutoxy)-2-(8-aminooctanamido)-N-(4-pheno...) Show SMILES NCCCCCCCC(=O)Nc1ccc(OCCCCN)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C31H40N4O4/c32-20-8-3-1-2-7-13-30(36)35-29-19-18-27(38-22-10-9-21-33)23-28(29)31(37)34-24-14-16-26(17-15-24)39-25-11-5-4-6-12-25/h4-6,11-12,14-19,23H,1-3,7-10,13,20-22,32-33H2,(H,34,37)(H,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304181 (5-(4-Aminobutoxy)-2-(6-aminohexanamido)-N-(4-pheno...) Show SMILES NCCCCCC(=O)Nc1ccc(OCCCCN)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H36N4O4/c30-18-6-2-5-11-28(34)33-27-17-16-25(36-20-8-7-19-31)21-26(27)29(35)32-22-12-14-24(15-13-22)37-23-9-3-1-4-10-23/h1,3-4,9-10,12-17,21H,2,5-8,11,18-20,30-31H2,(H,32,35)(H,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295706 (3-{4-[(2,2-Diphenyl-ethylamino)-methyl]-phenoxy}-p...) Show SMILES NCCCOc1ccc(CNCC(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C24H28N2O/c25-16-7-17-27-23-14-12-20(13-15-23)18-26-19-24(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-6,8-15,24,26H,7,16-19,25H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295704 (3-{4-[(Benzhydryl-amino)-methyl]-phenoxy}-propylam...) Show SMILES NCCCOc1ccc(CNC(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C23H26N2O/c24-16-7-17-26-22-14-12-19(13-15-22)18-25-23(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-6,8-15,23,25H,7,16-18,24H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50295698 (2-(3-Amino-propoxy)-N-(6-phenoxy-benzothiazol-2-yl...) Show SMILES NCCCOc1ccccc1C(=O)Nc1nc2ccc(Oc3ccccc3)cc2s1 Show InChI InChI=1S/C23H21N3O3S/c24-13-6-14-28-20-10-5-4-9-18(20)22(27)26-23-25-19-12-11-17(15-21(19)30-23)29-16-7-2-1-3-8-16/h1-5,7-12,15H,6,13-14,24H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Inhibition of rat neuronal Cav2.2 channel				Bioorg Med Chem Lett 19: 2763-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.130 BindingDB Entry DOI: 10.7270/Q2MC9029
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304191 (2-(6-Aminohexanamido)-5-(3-aminopropoxy)-N-(4-phen...) Show SMILES NCCCCCC(=O)Nc1ccc(OCCCN)cc1C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H34N4O4/c29-17-6-2-5-10-27(33)32-26-16-15-24(35-19-7-18-30)20-25(26)28(34)31-21-11-13-23(14-12-21)36-22-8-3-1-4-9-22/h1,3-4,8-9,11-16,20H,2,5-7,10,17-19,29-30H2,(H,31,34)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50304183 (2-(5-Guanidinopentanamido)-5-(3-guanidinopropoxy)-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(-[#8]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])cc1-[#6](=O)-[#7]-c1ccc(-[#8]-c2ccccc2)cc1 Show InChI InChI=1S/C29H36N8O4/c30-28(31)34-16-5-4-9-26(38)37-25-15-14-23(40-18-6-17-35-29(32)33)19-24(25)27(39)36-20-10-12-22(13-11-20)41-21-7-2-1-3-8-21/h1-3,7-8,10-15,19H,4-6,9,16-18H2,(H,36,39)(H,37,38)(H4,30,31,34)(H4,32,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation counting				Bioorg Med Chem 17: 6659-70 (2009) Article DOI: 10.1016/j.bmc.2009.07.063 BindingDB Entry DOI: 10.7270/Q2K937M3
					More data for this Ligand-Target Pair