Compile Data Set for Download or QSAR

Found 137 hits of ec50 for UniProtKB: P29990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Dengue virus 2)	BDBM514196 (US11053196, Compound 4B) Show SMILES COc1cc(N[C+](C(=O)N2CCc3c2cc(OC(F)(F)F)cc3C)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0570	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514148 (US11053196, Compound 2B) Show SMILES COc1cc(N[C+](C(=O)N2CCc3c2cc(cc3C)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0780	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514203 (US11053196, Compound 7A-D) Show SMILES COc1cc(N[C+](C(=O)N2CCc3ccc(OC(F)(F)F)cc23)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514145 (US11053196, Compound 1B) Show SMILES COc1cc(N[C+](C(=O)N2CCc3ccc(cc23)S(F)(F)(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514197 (4-(3-((1-(4-chlorophenyl)-2-(5-fluoro-6-(trifluoro...) Show SMILES COc1cc(NC(C(=O)N2CCc3cc(F)c(OC(F)(F)F)cc23)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514194 (4-(3-((1-(4-chlorophenyl)-2-(4-methyl-6-(trifluoro...) Show SMILES COc1cc(NC(C(=O)N2CCc3c2cc(OC(F)(F)F)cc3C)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514183 (US11053196, Compound 3B) Show SMILES COc1cc(N[C+](C(=O)N2CCc3cc(F)c(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514199 (US11053196, Compound 5B) Show SMILES COc1cc(N[C+](C(=O)N2CCc3cc(F)c(OC(F)(F)F)cc23)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514205 (4-(3-((1-(4-chloro-2-(2-hydroxyethoxy)phenyl)-2-ox...) Show SMILES COc1cc(NC(C(=O)N2CCc3ccc(OC(F)(F)F)cc23)c2ccc(Cl)cc2OCCO)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514210 (4-(3-((1-(4-chlorophenyl)-2-oxo-2-(6-((trifluorome...) Show SMILES COc1cc(NC(C(=O)N2CCc3ccc(SC(F)(F)F)cc23)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514208 (US11053196, Compound 10A) Show SMILES COc1cc(N[C+](C(=O)N2CCc3sc(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514146 (4-(3-((1-(4-chlorophenyl)-2-(4-methyl-6-(trifluoro...) Show SMILES COc1cc(NC(C(=O)N2CCc3c2cc(cc3C)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514202 (US11053196, Compound 6B) Show SMILES COc1cc(N[C+](C(=O)N2CCc3ccc(OC(F)(F)F)cc23)c2ccc(F)cc2OC)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.390	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514207 (4-(3-((1-(4-chlorophenyl)-2-oxo-2-(2-(trifluoromet...) Show SMILES COc1cc(NC(C(=O)N2CCc3sc(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.520	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514178 (4-(3-((1-(4-chlorophenyl)-2-(5-fluoro-6-(trifluoro...) Show SMILES COc1cc(NC(C(=O)N2CCc3cc(F)c(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.560	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514200 (4-(3-((1-(4-fluoro-2-methoxyphenyl)-2-oxo-2-(6-(tr...) Show SMILES COc1cc(NC(C(=O)N2CCc3ccc(OC(F)(F)F)cc23)c2ccc(F)cc2OC)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.630	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514142 (4-(3-((1-(4-chlorophenyl)-2-oxo-2-(6-(pentafluoro-...) Show SMILES COc1cc(NC(C(=O)N2CCc3ccc(cc23)S(F)(F)(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.640	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514206 (4-(3-((1-(4-chlorophenyl)-2-(5-methoxy-6-(trifluor...) Show SMILES COc1cc(NC(C(=O)N2CCc3nc(OC)c(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.990	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514144 (US11053196, Compound 1A) Show SMILES COc1cc(N[C-](C(=O)N2CCc3ccc(cc23)S(F)(F)(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514198 (US11053196, Compound 5A) Show SMILES COc1cc(N[C-](C(=O)N2CCc3cc(F)c(OC(F)(F)F)cc23)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514195 (US11053196, Compound 4A) Show SMILES COc1cc(N[C-](C(=O)N2CCc3c2cc(OC(F)(F)F)cc3C)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514147 (US11053196, Compound 2A) Show SMILES COc1cc(N[C-](C(=O)N2CCc3c2cc(cc3C)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514204 (US11053196, Compound 7B-D) Show SMILES COc1cc(N[C-](C(=O)N2CCc3ccc(OC(F)(F)F)cc23)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514179 (US11053196, Compound 3A) Show SMILES COc1cc(N[C-](C(=O)N2CCc3cc(F)c(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514209 (US11053196, Compound 10B) Show SMILES COc1cc(N[C-](C(=O)N2CCc3sc(cc23)C(F)(F)F)c2ccc(Cl)cc2)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM514201 (US11053196, Compound 6A) Show SMILES COc1cc(N[C-](C(=O)N2CCc3ccc(OC(F)(F)F)cc23)c2ccc(F)cc2OC)cc(OCCCC(O)=O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
TBA					Assay Description The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NK3J5C
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567933 (CHEMBL4855476) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(cc2)C(=O)c2ccccc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50542799 (CHEMBL4649655) Show SMILES OC(=O)C(F)(F)F.CCCCCC(=O)N[C@H](C(=O)NCc1ccc(NC(N)=N)cc1)c1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C29H35N5O3.C2HF3O2/c1-2-3-5-10-26(35)34-27(28(36)32-19-21-11-15-24(16-12-21)33-29(30)31)23-13-17-25(18-14-23)37-20-22-8-6-4-7-9-22;3-2(4,5)1(6)7/h4,6-9,11-18,27H,2-3,5,10,19-20H2,1H3,(H,32,36)(H,34,35)(H4,30,31,33);(H,6,7)/t27-;/m0./s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
Heidelberg University Curated by ChEMBL					Assay Description Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...				J Med Chem 63: 8179-8197 (2020) Article DOI: 10.1021/acs.jmedchem.0c00413 BindingDB Entry DOI: 10.7270/Q26H4N01
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50542807 (CHEMBL4632524) Show SMILES OC(=O)C(F)(F)F.CCCCCCC(=O)N[C@H](C(=O)NCc1ccc(NC(N)=N)cc1)c1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H37N5O3.C2HF3O2/c1-2-3-4-8-11-27(36)35-28(29(37)33-20-22-12-16-25(17-13-22)34-30(31)32)24-14-18-26(19-15-24)38-21-23-9-6-5-7-10-23;3-2(4,5)1(6)7/h5-7,9-10,12-19,28H,2-4,8,11,20-21H2,1H3,(H,33,37)(H,35,36)(H4,31,32,34);(H,6,7)/t28-;/m0./s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a
Heidelberg University Curated by ChEMBL					Assay Description Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...				J Med Chem 63: 8179-8197 (2020) Article DOI: 10.1021/acs.jmedchem.0c00413 BindingDB Entry DOI: 10.7270/Q26H4N01
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50592883 (CHEMBL5204060) Show SMILES OB1OCc2ccc(NC(=O)c3cccc(OCC4CCCCC4)c3)cc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114585 BindingDB Entry DOI: 10.7270/Q2445RGH
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567928 (CHEMBL4859686) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567923 (CHEMBL4858512) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3ccccc3)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50542808 (CHEMBL4641383) Show SMILES OC(=O)C(F)(F)F.CCCCCCCC(=O)N[C@H](C(=O)NCc1ccc(NC(N)=N)cc1)c1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C31H39N5O3.C2HF3O2/c1-2-3-4-5-9-12-28(37)36-29(30(38)34-21-23-13-17-26(18-14-23)35-31(32)33)25-15-19-27(20-16-25)39-22-24-10-7-6-8-11-24;3-2(4,5)1(6)7/h6-8,10-11,13-20,29H,2-5,9,12,21-22H2,1H3,(H,34,38)(H,36,37)(H4,32,33,35);(H,6,7)/t29-;/m0./s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	830	n/a	n/a	n/a	n/a
Heidelberg University Curated by ChEMBL					Assay Description Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...				J Med Chem 63: 8179-8197 (2020) Article DOI: 10.1021/acs.jmedchem.0c00413 BindingDB Entry DOI: 10.7270/Q26H4N01
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567926 (CHEMBL4867213) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3ccc(cc3)C#N)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567914 (CHEMBL4874769) Show SMILES NC(=O)c1ccc(CNC(=O)[C@@H](NC(=O)c2ccc(Oc3ccccc3)cc2)c2ccc(OCc3ccccc3)cc2)cc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567929 (CHEMBL4851091) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3cccc(Cl)c3)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50592879 (CHEMBL5201148) Show SMILES COc1cccc(COc2cccc(c2)C(=O)Nc2ccc3COB(O)c3c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114585 BindingDB Entry DOI: 10.7270/Q2445RGH
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567927 (CHEMBL4859856) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567939 (CHEMBL4853944) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(cc2)-c2ccc(Cl)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567934 (CHEMBL4857446) Show SMILES COc1cccc(COc2ccc(cc2)[C@H](NC(=O)c2ccc(cc2)C(=O)c2ccccc2)C(=O)Nc2cccc(c2)C(N)=O)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567930 (CHEMBL4847125) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3ccc4OCOc4c3)cc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567937 (CHEMBL4863404) Show SMILES Cc1ccc(C)c(OCCCC(C)(C)C(=O)N[C@H](C(=O)Nc2cccc(c2)C(N)=O)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567938 (CHEMBL4875828) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(cc2)-c2ccccc2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567924 (CHEMBL4864503) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2cccc(Oc3ccccc3)c2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567940 (CHEMBL4875560) Show SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(cc2)-c2ccco2)c2ccc(OCc3ccccc3)cc2)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567921 (CHEMBL4863273) Show SMILES COc1cccc(COc2ccc(cc2)[C@H](NC(=O)c2ccc(Oc3ccccc3)cc2)C(=O)Nc2cccc(c2)C(N)=O)c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50542814 (CHEMBL4646812) Show SMILES OC(=O)C(F)(F)F.NC(=N)Nc1ccc(CNC(=O)[C@@H](NC(=O)c2ccc(OCc3ccccc3)cc2)c2ccc(OCc3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C37H35N5O4.C2HF3O2/c38-37(39)41-31-17-11-26(12-18-31)23-40-36(44)34(29-13-19-32(20-14-29)45-24-27-7-3-1-4-8-27)42-35(43)30-15-21-33(22-16-30)46-25-28-9-5-2-6-10-28;3-2(4,5)1(6)7/h1-22,34H,23-25H2,(H,40,44)(H,42,43)(H4,38,39,41);(H,6,7)/t34-;/m0./s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Heidelberg University Curated by ChEMBL					Assay Description Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...				J Med Chem 63: 8179-8197 (2020) Article DOI: 10.1021/acs.jmedchem.0c00413 BindingDB Entry DOI: 10.7270/Q26H4N01
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50542811 (CHEMBL4646053) Show SMILES OC(=O)C(F)(F)F.NC(=N)Nc1ccc(CNC(=O)[C@@H](NC(=O)c2ccc(OC3CCCCC3)cc2)c2ccc(OCc3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C36H39N5O4.C2HF3O2/c37-36(38)40-29-17-11-25(12-18-29)23-39-35(43)33(27-13-19-30(20-14-27)44-24-26-7-3-1-4-8-26)41-34(42)28-15-21-32(22-16-28)45-31-9-5-2-6-10-31;3-2(4,5)1(6)7/h1,3-4,7-8,11-22,31,33H,2,5-6,9-10,23-24H2,(H,39,43)(H,41,42)(H4,37,38,40);(H,6,7)/t33-;/m0./s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Heidelberg University Curated by ChEMBL					Assay Description Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...				J Med Chem 63: 8179-8197 (2020) Article DOI: 10.1021/acs.jmedchem.0c00413 BindingDB Entry DOI: 10.7270/Q26H4N01
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567925 (CHEMBL4848292) Show SMILES COc1ccccc1Oc1ccc(cc1)C(=O)N[C@H](C(=O)Nc1cccc(c1)C(N)=O)c1ccc(OCc2ccccc2)cc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2)	BDBM50567917 (CHEMBL4869395) Show SMILES CCCCCCCC(=O)N[C@H](C(=O)Nc1cccc(c1)C(N)=O)c1ccc(OCc2ccccc2)cc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02042 BindingDB Entry DOI: 10.7270/Q2280CDX
					More data for this Ligand-Target Pair

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