Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protective antigen (Bacillus anthracis) | BDBM50398482 (CHEMBL2179142) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of matrix metalloprotease activated Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells compound co-treated for 5 ... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398483 (CHEMBL2179141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of matrix metalloprotease activated Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells compound co-treated for 5 ... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398482 (CHEMBL2179142) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells compound co-treated for 5 hrs with antigen measured after 4... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398483 (CHEMBL2179141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells compound co-treated for 5 hrs with antigen measured after 4... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398483 (CHEMBL2179141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells compound co-treated for 5 hrs with antigen measured after... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398482 (CHEMBL2179142) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells compound co-treated for 5 hrs with antigen measured after... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398482 (CHEMBL2179142) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells compound co-treated for 5 hrs with antigen by MTT assay i... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protective antigen (Bacillus anthracis) | BDBM50398483 (CHEMBL2179141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells compound co-treated for 5 hrs with antigen by MTT assay i... | J Med Chem 55: 7998-8006 (2012) Article DOI: 10.1021/jm300804e BindingDB Entry DOI: 10.7270/Q2ZP4786 | |||||||||||
More data for this Ligand-Target Pair |