Compile Data Set for Download or QSAR

Found 6 hits of ec50 for UniProtKB: P99999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome c (Homo sapiens)	BDBM50486083 (CHEMBL2203815) Show SMILES NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)[C@@H]1CC(=O)N(CCc2ccc(Cl)cc2Cl)CC(=O)N1CCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C39H38Cl4N4O4/c40-30-13-11-28(33(42)21-30)15-18-45-25-38(50)47(20-17-32(26-7-3-1-4-8-26)27-9-5-2-6-10-27)35(23-37(45)49)39(51)46(24-36(44)48)19-16-29-12-14-31(41)22-34(29)43/h1-14,21-22,32,35H,15-20,23-25H2,(H2,44,48)/t35-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
Instituto de Qu£mica Avanzada de Catalu£a Curated by ChEMBL					Assay Description Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...				Bioorg Med Chem Lett 22: 7097-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.078 BindingDB Entry DOI: 10.7270/Q2SB48M3
					More data for this Ligand-Target Pair
Cytochrome c (Homo sapiens)	BDBM50486085 (CHEMBL2203816) Show SMILES NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)[C@H]1CC(=O)N(CCc2ccc(Cl)cc2Cl)CC(=O)N1CCC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C39H38Cl4N4O4/c40-30-13-11-28(33(42)21-30)15-18-45-25-38(50)47(20-17-32(26-7-3-1-4-8-26)27-9-5-2-6-10-27)35(23-37(45)49)39(51)46(24-36(44)48)19-16-29-12-14-31(41)22-34(29)43/h1-14,21-22,32,35H,15-20,23-25H2,(H2,44,48)/t35-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a
Instituto de Qu£mica Avanzada de Catalu£a Curated by ChEMBL					Assay Description Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...				Bioorg Med Chem Lett 22: 7097-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.078 BindingDB Entry DOI: 10.7270/Q2SB48M3
					More data for this Ligand-Target Pair
Cytochrome c (Homo sapiens)	BDBM50486084 (CHEMBL252122) Show SMILES NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)C1CC(=O)N(CCc2ccc(Cl)cc2Cl)CC(=O)N1CCC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C39H38Cl4N4O4/c40-30-13-11-28(33(42)21-30)15-18-45-25-38(50)47(20-17-32(26-7-3-1-4-8-26)27-9-5-2-6-10-27)35(23-37(45)49)39(51)46(24-36(44)48)19-16-29-12-14-31(41)22-34(29)43/h1-14,21-22,32,35H,15-20,23-25H2,(H2,44,48)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a
Instituto de Qu£mica Avanzada de Catalu£a Curated by ChEMBL					Assay Description Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...				Bioorg Med Chem Lett 22: 7097-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.078 BindingDB Entry DOI: 10.7270/Q2SB48M3
					More data for this Ligand-Target Pair
Cytochrome c (Homo sapiens)	BDBM50486086 (CHEMBL2203814) Show SMILES NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)CC1N(CCC(c2ccccc2)c2ccccc2)C(=O)CN(CCc2ccc(Cl)cc2Cl)C1=O Show InChI InChI=1S/C39H38Cl4N4O4/c40-30-13-11-28(33(42)21-30)15-18-45(24-36(44)48)37(49)23-35-39(51)46(19-16-29-12-14-31(41)22-34(29)43)25-38(50)47(35)20-17-32(26-7-3-1-4-8-26)27-9-5-2-6-10-27/h1-14,21-22,32,35H,15-20,23-25H2,(H2,44,48)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a
Instituto de Qu£mica Avanzada de Catalu£a Curated by ChEMBL					Assay Description Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...				Bioorg Med Chem Lett 22: 7097-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.078 BindingDB Entry DOI: 10.7270/Q2SB48M3
					More data for this Ligand-Target Pair
Cytochrome c (Homo sapiens)	BDBM50486081 (CHEMBL2203812) Show SMILES NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)C[C@@H]1N(CCC(c2ccccc2)c2ccccc2)C(=O)CN(CCc2ccc(Cl)cc2Cl)C1=O |r| Show InChI InChI=1S/C39H38Cl4N4O4/c40-30-13-11-28(33(42)21-30)15-18-45(24-36(44)48)37(49)23-35-39(51)46(19-16-29-12-14-31(41)22-34(29)43)25-38(50)47(35)20-17-32(26-7-3-1-4-8-26)27-9-5-2-6-10-27/h1-14,21-22,32,35H,15-20,23-25H2,(H2,44,48)/t35-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.39E+4	n/a	n/a	n/a	n/a
Instituto de Qu£mica Avanzada de Catalu£a Curated by ChEMBL					Assay Description Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...				Bioorg Med Chem Lett 22: 7097-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.078 BindingDB Entry DOI: 10.7270/Q2SB48M3
					More data for this Ligand-Target Pair
Cytochrome c (Homo sapiens)	BDBM50486082 (CHEMBL2203813) Show SMILES NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)C[C@H]1N(CCC(c2ccccc2)c2ccccc2)C(=O)CN(CCc2ccc(Cl)cc2Cl)C1=O |r| Show InChI InChI=1S/C39H38Cl4N4O4/c40-30-13-11-28(33(42)21-30)15-18-45(24-36(44)48)37(49)23-35-39(51)46(19-16-29-12-14-31(41)22-34(29)43)25-38(50)47(35)20-17-32(26-7-3-1-4-8-26)27-9-5-2-6-10-27/h1-14,21-22,32,35H,15-20,23-25H2,(H2,44,48)/t35-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a
Instituto de Qu£mica Avanzada de Catalu£a Curated by ChEMBL					Assay Description Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...				Bioorg Med Chem Lett 22: 7097-9 (2012) Article DOI: 10.1016/j.bmcl.2012.09.078 BindingDB Entry DOI: 10.7270/Q2SB48M3
					More data for this Ligand-Target Pair