Compile Data Set for Download or QSAR

Found 4 hits of ic50 for UniProtKB: Q05586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2D (Homo sapiens (Human))	BDBM50498430 (CHEMBL3594112) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H34O4S.C5H5N/c1-13-4-7-17-16-6-5-14-12-15(24-25(21,22)23)8-10-20(14,3)18(16)9-11-19(13,17)2;1-2-4-6-5-3-1/h13-18H,4-12H2,1-3H3,(H,21,22,23);1-5H/t13-,14+,15+,16-,17-,18-,19+,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2D receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (Homo sapiens (Human))	BDBM409486 (N-Cyclopropyl-2-[6-[3-(trifluoromethyl)phenyl]pyrr...) Show SMILES FC(F)(F)c1cccc(c1)-c1cnc2ccn(CC(=O)NC3CC3)c2c1 Show InChI InChI=1S/C19H16F3N3O/c20-19(21,22)14-3-1-2-12(8-14)13-9-17-16(23-10-13)6-7-25(17)11-18(26)24-15-4-5-15/h1-3,6-10,15H,4-5,11H2,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...				ACS Med Chem Lett 10: 261-266 (2019) Article DOI: 10.1021/acsmedchemlett.8b00542 BindingDB Entry DOI: 10.7270/Q2B85CG6
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (Homo sapiens (Human))	BDBM436689 (N-Cyclopropyl-2-[2-oxo-6-[3-(trifluoromethyl)pheny...) Show SMILES FC(F)(F)c1cccc(c1)-c1cnc2[nH]c(=O)n(CC(=O)NC3CC3)c2c1 Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)12-3-1-2-10(6-12)11-7-14-16(22-8-11)24-17(27)25(14)9-15(26)23-13-4-5-13/h1-3,6-8,13H,4-5,9H2,(H,23,26)(H,22,24,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant human GluN1a/GluN2D expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...				ACS Med Chem Lett 10: 261-266 (2019) Article DOI: 10.1021/acsmedchemlett.8b00542 BindingDB Entry DOI: 10.7270/Q2B85CG6
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (Homo sapiens (Human))	BDBM50259886 (CHEMBL2333943) Show SMILES OC(=O)c1cc2cc(Br)ccc2oc1=O Show InChI InChI=1S/C10H5BrO4/c11-6-1-2-8-5(3-6)4-7(9(12)13)10(14)15-8/h1-4H,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of GluN1a/GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glutamate/glyc...				J Med Chem 62: 3-23 (2019) Article DOI: 10.1021/acs.jmedchem.7b01640 BindingDB Entry DOI: 10.7270/Q2N019RG
					More data for this Ligand-Target Pair