Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM18512 (5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada. Curated by ChEMBL | Assay Description Inhibition of beta-N-acetylhexosaminidase (unknown origin) | J Med Chem 58: 4483-93 (2015) Article DOI: 10.1021/jm5017895 BindingDB Entry DOI: 10.7270/Q28054CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50190644 (CHEMBL3983808) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Barcelona Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate ass... | Eur J Med Chem 121: 926-938 (2016) Article DOI: 10.1016/j.ejmech.2015.10.038 BindingDB Entry DOI: 10.7270/Q2542QJ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit alpha/beta (Homo sapiens (Human)) | BDBM50190645 (CHEMBL3982827) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Barcelona Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate ass... | Eur J Med Chem 121: 926-938 (2016) Article DOI: 10.1016/j.ejmech.2015.10.038 BindingDB Entry DOI: 10.7270/Q2542QJ5 | |||||||||||
More data for this Ligand-Target Pair |