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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: Q01844   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Friend leukemia integration 1 transcription factor/RNA-binding protein EWS


(Homo sapiens-Homo sapiens (Human))		BDBM50497658
PNG
(CHEMBL3360384)
Show SMILES COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(OC)ccc2OC
Show InChI InChI=1S/C19H19NO6/c1-24-12-6-4-11(5-7-12)13(21)10-19(23)16-14(25-2)8-9-15(26-3)17(16)20-18(19)22/h4-9,23H,10H2,1-3H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 770n/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of transcriptional activity of full-length EWS-FLI1 (unknown origin) expressed in COS7 cells by NR0B1-luciferase reporter gene assay

J Med Chem 57: 10290-303 (2014)


Article DOI: 10.1021/jm501372p
BindingDB Entry DOI: 10.7270/Q29G5QTK
More data for this
Ligand-Target Pair