Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit A/B (Staphylococcus aureus subsp. aureus Mu50) | BDBM21690 (1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wockhardt Limited Curated by ChEMBL | Assay Description Inhibition of supercoiling activity of DNA gyrase from Staphylococcus aureus ISP 794 | J Med Chem 48: 5232-42 (2005) Article DOI: 10.1021/jm050035f BindingDB Entry DOI: 10.7270/Q2K0771W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |