Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 105897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM105897 (US10047086, 141 | US10640503, Example 141 | US9695...) Show SMILES CNC(=O)c1ccc(cn1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H28N8O/c1-29-27(36)22-9-8-20(15-31-22)25-24(19-6-4-18(14-28)5-7-19)32-26(23-16-30-17-35(23)25)34-12-10-21(11-13-34)33(2)3/h4-9,15-17,21H,10-13H2,1-3H3,(H,29,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105897 (US10047086, 141 | US10640503, Example 141 | US9695...) Show SMILES CNC(=O)c1ccc(cn1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H28N8O/c1-29-27(36)22-9-8-20(15-31-22)25-24(19-6-4-18(14-28)5-7-19)32-26(23-16-30-17-35(23)25)34-12-10-21(11-13-34)33(2)3/h4-9,15-17,21H,10-13H2,1-3H3,(H,29,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105897 (US10047086, 141 | US10640503, Example 141 | US9695...) Show SMILES CNC(=O)c1ccc(cn1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H28N8O/c1-29-27(36)22-9-8-20(15-31-22)25-24(19-6-4-18(14-28)5-7-19)32-26(23-16-30-17-35(23)25)34-12-10-21(11-13-34)33(2)3/h4-9,15-17,21H,10-13H2,1-3H3,(H,29,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair