Found 112 hits of ic50 for monomerid = 11682 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and ... |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116194 BindingDB Entry DOI: 10.7270/Q2154MTC |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of BChE (unknown origin) |
Eur J Med Chem 156: 598-617 (2018)
Article DOI: 10.1016/j.ejmech.2018.07.033 BindingDB Entry DOI: 10.7270/Q27W6FW2 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BuChE using S-butyrylthiocholine as substrate preincubated for 30 mins followed by substrate addition and measured after 25 mins ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.113059 BindingDB Entry DOI: 10.7270/Q2KP85V3 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Mus musculus (Mouse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Medical Sciences and Peking Union Medical College
Curated by ChEMBL
| Assay Description Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to control |
Eur J Med Chem 168: 207-220 (2019)
Article DOI: 10.1016/j.ejmech.2019.02.053 BindingDB Entry DOI: 10.7270/Q2DN48JW |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113735 BindingDB Entry DOI: 10.7270/Q2H41W7X |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition ... |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116194 BindingDB Entry DOI: 10.7270/Q2154MTC |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Hu'nan University
Curated by ChEMBL
| Assay Description Inhibition of butyrylcholinesterase (unknown origin) using butyrylthiocholine iodide as substrate after 25 mins by Ellmann method |
Eur J Med Chem 126: 810-822 (2017)
Article DOI: 10.1016/j.ejmech.2016.12.003 BindingDB Entry DOI: 10.7270/Q2HH6N9M |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human serum BChE using butyrylthiocholine as substrate by Ellman's assay |
Eur J Med Chem 166: 90-107 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.030 BindingDB Entry DOI: 10.7270/Q2VQ363K |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human BuChe using S-butyrylthiocholine iodide as substrate measured after 7 mins by Ellman's method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113541 BindingDB Entry DOI: 10.7270/Q25D8WNM |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum University of Bologna
Curated by ChEMBL
| Assay Description Inhibition of human serum BuChE using acetylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's... |
J Med Chem 59: 6387-406 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00609 BindingDB Entry DOI: 10.7270/Q21G0P6Q |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
Julius Maximilian University W£rzburg
Curated by ChEMBL
| Assay Description Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's... |
J Med Chem 62: 9116-9140 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01012 BindingDB Entry DOI: 10.7270/Q2M3301T |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d2md00087c BindingDB Entry DOI: 10.7270/Q2W66QRK |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of human BuChE using butyrylthiocholine as substrate after 1 min by Ellman's method |
J Med Chem 61: 119-139 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01086 BindingDB Entry DOI: 10.7270/Q2S75JRJ |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
South China University of Technology
Curated by ChEMBL
| Assay Description Inhibition of human serum BChE using S-Butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's met... |
Bioorg Med Chem 25: 360-371 (2017)
Article DOI: 10.1016/j.bmc.2016.11.002 BindingDB Entry DOI: 10.7270/Q2NK3H15 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 495 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by... |
J Med Chem 59: 7683-9 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00356 BindingDB Entry DOI: 10.7270/Q2959N29 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University
Curated by ChEMBL
| Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by ... |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111598 BindingDB Entry DOI: 10.7270/Q24F1V59 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by addition of substrate ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112273 BindingDB Entry DOI: 10.7270/Q2T157BP |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 678 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pisa
Curated by ChEMBL
| Assay Description Inhibition concentration against human adenosine kinase |
Eur J Med Chem 141: 232-239 (2017)
Article DOI: 10.1016/j.ejmech.2017.10.006 BindingDB Entry DOI: 10.7270/Q2377C79 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 785 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description Inhibition of equine serum BChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition and measured f... |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115324 BindingDB Entry DOI: 10.7270/Q2VH5SDB |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 803 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human BuChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assay |
J Med Chem 59: 7683-9 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00356 BindingDB Entry DOI: 10.7270/Q2959N29 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of AChE in human erythrocytes preincubated for 60 mins followed by substrate addition by Ellman's method |
J Med Chem 62: 8881-8914 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00017 BindingDB Entry DOI: 10.7270/Q27084PF |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of rat synaptosome SERT |
J Med Chem 62: 8881-8914 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00017 BindingDB Entry DOI: 10.7270/Q27084PF |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bezmialem Vakif University
Curated by ChEMBL
| Assay Description Inhibition of horse serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's meth... |
Bioorg Med Chem 25: 1352-1363 (2017)
Article DOI: 10.1016/j.bmc.2016.12.037 BindingDB Entry DOI: 10.7270/Q2W95CC5 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
| Assay Description Inhibition of human serum butyrylcholinesterase using BTCI as substrate pre-incubated for 10 mins followed by substrate addition and measured for 6 m... |
Eur J Med Chem 167: 510-524 (2019)
Article DOI: 10.1016/j.ejmech.2019.02.030 BindingDB Entry DOI: 10.7270/Q2JD5192 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of equine serum BuChE using BTC as substrate after 15 mins by Ellman's method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112265 BindingDB Entry DOI: 10.7270/Q2W099J0 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129037 BindingDB Entry DOI: 10.7270/Q2W381DJ |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BChE by Ellman's method |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115721 BindingDB Entry DOI: 10.7270/Q2J106T5 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's metho... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111707 BindingDB Entry DOI: 10.7270/Q2833WM3 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Normal University
Curated by ChEMBL
| Assay Description Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as susbtrate preincubated for 6 mins followed by substrate addition measured up to... |
Eur J Med Chem 178: 726-739 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.026 BindingDB Entry DOI: 10.7270/Q2668HJZ |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114152 BindingDB Entry DOI: 10.7270/Q2445RKV |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Millia Islamia (Central University)
Curated by ChEMBL
| Assay Description Inhibition of equine serum BuChE preincubated for 5 mins followed by addition of butyrylthiocholine iodide as substrate measured after 2 mins by Ellm... |
Eur J Med Chem 119: 260-77 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.053 BindingDB Entry DOI: 10.7270/Q2319XT7 |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human BuchE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition by Ellman's method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112282 BindingDB Entry DOI: 10.7270/Q29P35CF |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d2md00087c BindingDB Entry DOI: 10.7270/Q2W66QRK |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Henan University
Curated by ChEMBL
| Assay Description Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition by Ellman's m... |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2019.115190 BindingDB Entry DOI: 10.7270/Q2FX7F1F |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum University of Bologna
Curated by ChEMBL
| Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ell... |
J Med Chem 59: 6387-406 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00609 BindingDB Entry DOI: 10.7270/Q21G0P6Q |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Julius Maximilian University W£rzburg
Curated by ChEMBL
| Assay Description Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's ... |
J Med Chem 62: 9116-9140 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01012 BindingDB Entry DOI: 10.7270/Q2M3301T |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human erythrocyte AChE using acetylthiocholine as substrate by Ellman's assay |
Eur J Med Chem 166: 90-107 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.030 BindingDB Entry DOI: 10.7270/Q2VQ363K |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.111707 BindingDB Entry DOI: 10.7270/Q2833WM3 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human AChE by Ellman's method |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115721 BindingDB Entry DOI: 10.7270/Q2J106T5 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
| Assay Description Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addi... |
Eur J Med Chem 167: 510-524 (2019)
Article DOI: 10.1016/j.ejmech.2019.02.030 BindingDB Entry DOI: 10.7270/Q2JD5192 |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of recombinant human AChE using acetylthiocholine as substrate after 1 min by Ellman's method |
J Med Chem 61: 119-139 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01086 BindingDB Entry DOI: 10.7270/Q2S75JRJ |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank
| n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113783 BindingDB Entry DOI: 10.7270/Q21V5JSC |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 2.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 5 mins followed by substrate addition and m... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113735 BindingDB Entry DOI: 10.7270/Q2H41W7X |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 2.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BuChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112415 BindingDB Entry DOI: 10.7270/Q27P9344 |
More data for this Ligand-Target Pair | |
Carboxylic ester hydrolase
(Rattus norvegicus (rat)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | Reactome pathway KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's method |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116074 BindingDB Entry DOI: 10.7270/Q2HX1HBN |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 3.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of AChE (unknown origin) |
Eur J Med Chem 156: 598-617 (2018)
Article DOI: 10.1016/j.ejmech.2018.07.033 BindingDB Entry DOI: 10.7270/Q27W6FW2 |
More data for this Ligand-Target Pair | |
Carboxylic ester hydrolase
(Rattus norvegicus (rat)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | Reactome pathway KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128574 BindingDB Entry DOI: 10.7270/Q22J6GXX |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM11682
(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 3.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China University of Technology
Curated by ChEMBL
| Assay Description Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's ... |
Bioorg Med Chem 25: 360-371 (2017)
Article DOI: 10.1016/j.bmc.2016.11.002 BindingDB Entry DOI: 10.7270/Q2NK3H15 |
More data for this Ligand-Target Pair | |