Found 14 hits of ic50 for monomerid = 13075 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Marburg
| Assay Description Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt... |
J Med Chem 45: 3588-602 (2002)
Article DOI: 10.1021/jm011112j BindingDB Entry DOI: 10.7270/Q2RJ4GQP |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
Curated by ChEMBL
| Assay Description Inhibition of hydratase-activity of human erythrocytes CA2 by CO2-hydration method |
Bioorg Med Chem 18: 930-8 (2010)
Article DOI: 10.1016/j.bmc.2009.11.031 BindingDB Entry DOI: 10.7270/Q2FQ9XK3 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
| Assay Description The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al.... |
J Enzyme Inhib Med Chem 26: 104-14 (2011)
Article DOI: 10.3109/14756361003733639 BindingDB Entry DOI: 10.7270/Q2PC318R |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
Curated by ChEMBL
| Assay Description Inhibition of hydratase-activity of CA1 from human erythrocytes by CO2-hydration method |
Bioorg Med Chem 18: 930-8 (2010)
Article DOI: 10.1016/j.bmc.2009.11.031 BindingDB Entry DOI: 10.7270/Q2FQ9XK3 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
| Assay Description The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al.... |
J Enzyme Inhib Med Chem 26: 104-14 (2011)
Article DOI: 10.3109/14756361003733639 BindingDB Entry DOI: 10.7270/Q2PC318R |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Dumlupinar University
| Assay Description The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate... |
J Enzyme Inhib Med Chem 26: 104-14 (2011)
Article DOI: 10.3109/14756361003733639 BindingDB Entry DOI: 10.7270/Q2PC318R |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
Curated by ChEMBL
| Assay Description Inhibition of esterase-activity of CA1 from human erythrocytes by spectrophotometry |
Bioorg Med Chem 18: 930-8 (2010)
Article DOI: 10.1016/j.bmc.2009.11.031 BindingDB Entry DOI: 10.7270/Q2FQ9XK3 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
Curated by ChEMBL
| Assay Description Inhibition of CA1 from human erythrocytes by Lineweaver-Burke analysis |
Bioorg Med Chem 18: 930-8 (2010)
Article DOI: 10.1016/j.bmc.2009.11.031 BindingDB Entry DOI: 10.7270/Q2FQ9XK3 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
| Assay Description The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. ... |
J Enzyme Inhib Med Chem 26: 104-14 (2011)
Article DOI: 10.3109/14756361003733639 BindingDB Entry DOI: 10.7270/Q2PC318R |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Dumlupinar University
| Assay Description The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate... |
J Enzyme Inhib Med Chem 26: 104-14 (2011)
Article DOI: 10.3109/14756361003733639 BindingDB Entry DOI: 10.7270/Q2PC318R |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
Curated by ChEMBL
| Assay Description Inhibition of esterase-activity of human erythrocytes CA2 by spectrophotometry |
Bioorg Med Chem 18: 930-8 (2010)
Article DOI: 10.1016/j.bmc.2009.11.031 BindingDB Entry DOI: 10.7270/Q2FQ9XK3 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
Curated by ChEMBL
| Assay Description Inhibition of human erythrocytes CA2 by Lineweaver-Burke analysis |
Bioorg Med Chem 18: 930-8 (2010)
Article DOI: 10.1016/j.bmc.2009.11.031 BindingDB Entry DOI: 10.7270/Q2FQ9XK3 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University
| Assay Description The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. ... |
J Enzyme Inhib Med Chem 26: 104-14 (2011)
Article DOI: 10.3109/14756361003733639 BindingDB Entry DOI: 10.7270/Q2PC318R |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (docked) |
CDGSH iron-sulfur domain-containing protein 1
(Homo sapiens (Human)) | BDBM13075
![PNG](/data/jpeg/tenK1/BindingDB_13075.png) (2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 ...)Show InChI InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
Patents
Similars
| | n/a | n/a | 4.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |