Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase mTOR (Homo sapiens (Human)) | BDBM178338 (US9120812, 123) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Sanofi US Patent | Assay Description The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin... | US Patent US9120812 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human)) | BDBM178338 (US9120812, 123) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Sanofi US Patent | Assay Description The test uses a lucifeurerin/luciferase system to measure the concentration of ATP and its consumption during the enzymatic reaction. The test is per... | US Patent US9120812 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M2D | |||||||||||
More data for this Ligand-Target Pair |