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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 221269   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma [258-518,Y502F]


(Homo sapiens (Human))		BDBM221269
PNG
(US9303015, 43)
Show SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(Cl)c(Nc3ccccc3)c(Cl)c2c1
Show InChI InChI=1S/C26H19Cl3N4O/c1-33-15-30-14-22(33)26(34,16-7-10-18(27)11-8-16)17-9-12-21-20(13-17)23(28)24(25(29)32-21)31-19-5-3-2-4-6-19/h2-15,31,34H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 880n/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...

US Patent US9303015 (2016)


BindingDB Entry DOI: 10.7270/Q29P30H5
More data for this
Ligand-Target Pair