Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human)) | BDBM228816![]() (5-Cl-PZA) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University at Albany | Assay Description Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha... | Chembiochem 18: 931-940 (2017) Article DOI: 10.1002/cbic.201600655 BindingDB Entry DOI: 10.7270/Q2CJ8CC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human)) | BDBM228816![]() (5-Cl-PZA) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist activity at oxytocin receptor in rat uterine strips assessed as inhibition of oxytocin-induced contraction | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human)) | BDBM228816![]() (5-Cl-PZA) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibition of human recombinant MGL | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human)) | BDBM228816![]() (5-Cl-PZA) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of His-tagged human SIRT6 expressed in Escherichia coli BL21(DE3) using Ac-p53 as substrate by fluorescence-based coupled-enzyme assay | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127215 BindingDB Entry DOI: 10.7270/Q2VT1WN9 | |||||||||||
More data for this Ligand-Target Pair |