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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 246863   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))
BDBM246863
PNG
(2-methylnicotinohydrazide | US10053463, 14)
Show SMILES Cc1ncccc1C(=O)NN
Show InChI InChI=1S/C7H9N3O/c1-5-6(7(11)10-8)3-2-4-9-5/h2-4H,8H2,1H3,(H,10,11)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 2.10n/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...


US Patent US10053463 (2018)


BindingDB Entry DOI: 10.7270/Q2FT8P24
More data for this
Ligand-Target Pair
P2X purinoceptor 7


(Mus musculus)
BDBM246863
PNG
(2-methylnicotinohydrazide | US10053463, 14)
Show SMILES Cc1ncccc1C(=O)NN
Show InChI InChI=1S/C7H9N3O/c1-5-6(7(11)10-8)3-2-4-9-5/h2-4H,8H2,1H3,(H,10,11)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 49.5n/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...


US Patent US10053463 (2018)


BindingDB Entry DOI: 10.7270/Q2FT8P24
More data for this
Ligand-Target Pair