Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM268520![]() (N-(7-((3-chloro-5-(trifluoromethoxy)phenoxy)methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.2 | n/a |
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent | Assay Description The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ... | US Patent US9550775 (2017) BindingDB Entry DOI: 10.7270/Q20C4XRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM268520![]() (N-(7-((3-chloro-5-(trifluoromethoxy)phenoxy)methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.33 | n/a | n/a | n/a | n/a | 7.2 | n/a |
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent | Assay Description The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ... | US Patent US9550775 (2017) BindingDB Entry DOI: 10.7270/Q20C4XRZ | |||||||||||
More data for this Ligand-Target Pair |