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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 307524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM307524
PNG
((S)-3-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC)CCC(O)=O)cc1OC |r|
Show InChI InChI=1S/C25H39N5O4/c1-5-7-20(11-13-31)28-24-21(17(3)27-25(26)29-24)15-19-9-8-18(14-22(19)34-4)16-30(6-2)12-10-23(32)33/h8-9,14,20,31H,5-7,10-13,15-16H2,1-4H3,(H,32,33)(H3,26,27,28,29)/t20-/m0/s1
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PC cid
PC sid
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n/an/a>1.00E+4n/an/an/an/an/an/a



Sumitomo Dainippon Pharma Co., Ltd.

US Patent


Assay Description
The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...


US Patent US10562861 (2020)


BindingDB Entry DOI: 10.7270/Q22F7QTT
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM307524
PNG
((S)-3-((4-((2-amino-4-(1-hydroxyhexan-3-ylamino)-6...)
Show SMILES CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(CC)CCC(O)=O)cc1OC |r|
Show InChI InChI=1S/C25H39N5O4/c1-5-7-20(11-13-31)28-24-21(17(3)27-25(26)29-24)15-19-9-8-18(14-22(19)34-4)16-30(6-2)12-10-23(32)33/h8-9,14,20,31H,5-7,10-13,15-16H2,1-4H3,(H,32,33)(H3,26,27,28,29)/t20-/m0/s1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>3.30E+4n/an/an/an/an/an/a



Sumitomo Dainippon Pharma Co., Ltd.

US Patent


Assay Description
Cell CultureThe hERG-expressing Chinese hamster ovary K1 (CHO) cells described by (Persson, Carlsson, Duker, & Jacobson, 2005) were grown to semi-con...


US Patent US10562861 (2020)


BindingDB Entry DOI: 10.7270/Q22F7QTT
More data for this
Ligand-Target Pair