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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 3139   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)
BDBM3139
PNG
(2-pyridinone deriv. 45 | 5-ethyl-3-{[(3-methoxypyr...)
Show SMILES CCc1cc(NCc2ncccc2OC)c(=O)[nH]c1C
Show InChI InChI=1S/C15H19N3O2/c1-4-11-8-12(15(19)18-10(11)2)17-9-13-14(20-3)6-5-7-16-13/h5-8,17H,4,9H2,1-3H3,(H,18,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.55E+3n/an/an/an/a8.2n/a



Merck Research Laboratories



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 36: 249-55 (1993)


Article DOI: 10.1021/jm00054a009
BindingDB Entry DOI: 10.7270/Q20863HM
More data for this
Ligand-Target Pair