Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 320544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320544 (US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...) Show SMILES Cc1nn(C)cc1-c1nc2n(C)c(nc2c(N2CCOCC2)c1F)C(=O)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C26H35FN8O3/c1-17-19(16-31(2)30-17)21-20(27)23(34-10-14-38-15-11-34)22-24(28-21)32(3)25(29-22)26(36)35-6-4-18(5-7-35)33-8-12-37-13-9-33/h16,18H,4-15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320544 (US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...) Show SMILES Cc1nn(C)cc1-c1nc2n(C)c(nc2c(N2CCOCC2)c1F)C(=O)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C26H35FN8O3/c1-17-19(16-31(2)30-17)21-20(27)23(34-10-14-38-15-11-34)22-24(28-21)32(3)25(29-22)26(36)35-6-4-18(5-7-35)33-8-12-37-13-9-33/h16,18H,4-15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human))	BDBM320544 (US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...) Show SMILES Cc1nn(C)cc1-c1nc2n(C)c(nc2c(N2CCOCC2)c1F)C(=O)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C26H35FN8O3/c1-17-19(16-31(2)30-17)21-20(27)23(34-10-14-38-15-11-34)22-24(28-21)32(3)25(29-22)26(36)35-6-4-18(5-7-35)33-8-12-37-13-9-33/h16,18H,4-15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Homo sapiens (Human))	BDBM320544 (US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...) Show SMILES Cc1nn(C)cc1-c1nc2n(C)c(nc2c(N2CCOCC2)c1F)C(=O)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C26H35FN8O3/c1-17-19(16-31(2)30-17)21-20(27)23(34-10-14-38-15-11-34)22-24(28-21)32(3)25(29-22)26(36)35-6-4-18(5-7-35)33-8-12-37-13-9-33/h16,18H,4-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM320544 (US10174035, Compound 87 | [5-(1,3-Dimethyl-1H-pyra...) Show SMILES Cc1nn(C)cc1-c1nc2n(C)c(nc2c(N2CCOCC2)c1F)C(=O)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C26H35FN8O3/c1-17-19(16-31(2)30-17)21-20(27)23(34-10-14-38-15-11-34)22-24(28-21)32(3)25(29-22)26(36)35-6-4-18(5-7-35)33-8-12-37-13-9-33/h16,18H,4-15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair