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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 354786   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 11


(Homo sapiens (Human))
BDBM354786
PNG
(6-(2,3- dihydrobenzo[b][1,4]dioxin- 6-yl)-1-(1H-in...)
Show SMILES O=c1[nH]c2ncc(nc2n1-c1ccc2[nH]ccc2c1)-c1ccc2OCCOc2c1
Show InChI InChI=1S/C21H15N5O3/c27-21-25-19-20(26(21)14-2-3-15-13(9-14)5-6-22-15)24-16(11-23-19)12-1-4-17-18(10-12)29-8-7-28-17/h1-6,9-11,22H,7-8H2,(H,23,25,27)
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of Rochester; Board of Regents of the University of Nebraska

US Patent


Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...


US Patent US10485800 (2019)


BindingDB Entry DOI: 10.7270/Q22B91DW
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11


(Homo sapiens (Human))
BDBM354786
PNG
(6-(2,3- dihydrobenzo[b][1,4]dioxin- 6-yl)-1-(1H-in...)
Show SMILES O=c1[nH]c2ncc(nc2n1-c1ccc2[nH]ccc2c1)-c1ccc2OCCOc2c1
Show InChI InChI=1S/C21H15N5O3/c27-21-25-19-20(26(21)14-2-3-15-13(9-14)5-6-22-15)24-16(11-23-19)12-1-4-17-18(10-12)29-8-7-28-17/h1-6,9-11,22H,7-8H2,(H,23,25,27)
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of Rochester

US Patent


Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...


US Patent US9814704 (2017)


BindingDB Entry DOI: 10.7270/Q27H1MRN
More data for this
Ligand-Target Pair