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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 397402   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3 [D835Y]


(Homo sapiens (Human))		BDBM397402
PNG
(US9987278, Compound Reference 12)
Show SMILES CCCNc1nc(NCCc2ccncc2)ncc1C(=O)Nc1cccc(NC(=O)CNC(=O)\C=C\CN2CCN(C)CC2)c1
Show InChI InChI=1S/C32H42N10O3/c1-3-12-34-30-27(22-37-32(40-30)35-15-11-24-9-13-33-14-10-24)31(45)39-26-7-4-6-25(21-26)38-29(44)23-36-28(43)8-5-16-42-19-17-41(2)18-20-42/h4-10,13-14,21-22H,3,11-12,15-20,23H2,1-2H3,(H,36,43)(H,38,44)(H,39,45)(H2,34,35,37,40)/b8-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.5n/an/an/an/an/an/a



BioCryst Pharmaceuticals



Assay Description
Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...

Bioorg Med Chem 17: 3934-58 (2009)


BindingDB Entry DOI: 10.7270/Q2J38VZJ
More data for this
Ligand-Target Pair