Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 444472   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444472 (US10662159, Example 63) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CC3(CC(C3)Oc3cccc(c3)C(F)(F)F)C1)C2=O Show InChI InChI=1S/C21H21F3N2O5/c1-19(2)14-15(19)17(28)26(16(14)27)31-18(29)25-9-20(10-25)7-13(8-20)30-12-5-3-4-11(6-12)21(22,23)24/h3-6,13-15H,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
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Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM444472 (US10662159, Example 63) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CC3(CC(C3)Oc3cccc(c3)C(F)(F)F)C1)C2=O Show InChI InChI=1S/C21H21F3N2O5/c1-19(2)14-15(19)17(28)26(16(14)27)31-18(29)25-9-20(10-25)7-13(8-20)30-12-5-3-4-11(6-12)21(22,23)24/h3-6,13-15H,7-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM444472 (US10662159, Example 63) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CC3(CC(C3)Oc3cccc(c3)C(F)(F)F)C1)C2=O Show InChI InChI=1S/C21H21F3N2O5/c1-19(2)14-15(19)17(28)26(16(14)27)31-18(29)25-9-20(10-25)7-13(8-20)30-12-5-3-4-11(6-12)21(22,23)24/h3-6,13-15H,7-10H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description hABHD6:Initial Fluorescent Inhibition Assay (3-Point)—In each well of a 96-well plate 8 μL of membrane fraction containing full-length hABHD6 (1...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444472 (US10662159, Example 63) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CC3(CC(C3)Oc3cccc(c3)C(F)(F)F)C1)C2=O Show InChI InChI=1S/C21H21F3N2O5/c1-19(2)14-15(19)17(28)26(16(14)27)31-18(29)25-9-20(10-25)7-13(8-20)30-12-5-3-4-11(6-12)21(22,23)24/h3-6,13-15H,7-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair