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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 446   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM446
PNG
(5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...)
Show SMILES CCCC1(CCc2ccc(O)cc2)CC(=O)C(Sc2cc(C)c(OS(=O)(=O)c3nccn3C)cc2C(C)(C)C)C(=O)O1
Show InChI InChI=1S/C31H38N2O7S2/c1-7-13-31(14-12-21-8-10-22(34)11-9-21)19-24(35)27(28(36)39-31)41-26-17-20(2)25(18-23(26)30(3,4)5)40-42(37,38)29-32-15-16-33(29)6/h8-11,15-18,27,34H,7,12-14,19H2,1-6H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research



Assay Description
Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...

J Med Chem 43: 843-58 (2000)


Article DOI: 10.1021/jm990281p
BindingDB Entry DOI: 10.7270/Q21N7Z9R
More data for this
Ligand-Target Pair