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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50015489   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM50015489
PNG
(CHEMBL3265011)
Show SMILES COc1ccc(Nc2nc(cn3ccnc23)-c2cc(ccc2C)C(N)=O)cc1OC
Show InChI InChI=1S/C22H21N5O3/c1-13-4-5-14(20(23)28)10-16(13)17-12-27-9-8-24-22(27)21(26-17)25-15-6-7-18(29-2)19(11-15)30-3/h4-12H,1-3H3,(H2,23,28)(H,25,26)
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n/an/a 466n/an/an/an/an/an/a



Gilead Sciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of full length Syk (unknown origin) using biotinylated peptide substrate

J Med Chem 57: 3856-73 (2014)


Article DOI: 10.1021/jm500228a
BindingDB Entry DOI: 10.7270/Q2B27WV1
More data for this
Ligand-Target Pair