Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50019949 (1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanit£ Curated by ChEMBL | Assay Description Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50% | J Med Chem 30: 1906-10 (1987) BindingDB Entry DOI: 10.7270/Q2DB82D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acetyltransferase Eis (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50019949 (1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1039/d1md00239b BindingDB Entry DOI: 10.7270/Q2417214 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50019949 (1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanit£ Curated by ChEMBL | Assay Description Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activity | J Med Chem 30: 1906-10 (1987) BindingDB Entry DOI: 10.7270/Q2DB82D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rattus norvegicus (rat)-RAT) | BDBM50019949 (1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Superiore di Sanit£ Curated by ChEMBL | Assay Description Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50% | J Med Chem 30: 1906-10 (1987) BindingDB Entry DOI: 10.7270/Q2DB82D1 | |||||||||||
More data for this Ligand-Target Pair |