BindingDB PrimarySearch

Found 7 hits of ic50 for monomerid = 50020891
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium- and chloride-dependent GABA transporter 1 (Homo sapiens (Human))	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibitory activity against human GABA transporter-1 (hGAT1)				J Med Chem 37: 2334-42 (1994) BindingDB Entry DOI: 10.7270/Q2P849XX
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	692	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians-University Munich Curated by ChEMBL					Assay Description Inhibition of mouse GAT1 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysis				Bioorg Med Chem 21: 3363-78 (2013) Article DOI: 10.1016/j.bmc.2013.02.056 BindingDB Entry DOI: 10.7270/Q23N269C
Ludwig-Maximilians-University Munich Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 3 (Mus musculus)	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians-University Munich Curated by ChEMBL					Assay Description Inhibition of mouse GAT3 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysis				Bioorg Med Chem 21: 3363-78 (2013) Article DOI: 10.1016/j.bmc.2013.02.056 BindingDB Entry DOI: 10.7270/Q23N269C
Ludwig-Maximilians-University Munich Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 2 (Mus musculus)	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.72E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians-University Munich Curated by ChEMBL					Assay Description Inhibition of mouse GAT2 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysis				Bioorg Med Chem 21: 3363-78 (2013) Article DOI: 10.1016/j.bmc.2013.02.056 BindingDB Entry DOI: 10.7270/Q23N269C
Ludwig-Maximilians-University Munich Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 2 (Rattus norvegicus)	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibitory activity against rat GABA transporter-2 (rGAT2)				J Med Chem 37: 2334-42 (1994) BindingDB Entry DOI: 10.7270/Q2P849XX
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 3 (Homo sapiens (Human))	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.99E+6	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibitory activity against human sodium and chloride dependent GABA transporter 3				J Med Chem 37: 2334-42 (1994) BindingDB Entry DOI: 10.7270/Q2P849XX
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM50020891 ((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.21E+6	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibition of human GABA transporter (hBGT-1) activity.				J Med Chem 37: 2334-42 (1994) BindingDB Entry DOI: 10.7270/Q2P849XX
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair