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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50023528   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50023528
PNG
(2,2-Dimethyl-propionic acid 4-[4-(2,2-dimethyl-pro...)
Show SMILES CC(C)(C)C(=O)Oc1ccc(Cc2ccc(OC(=O)C(C)(C)C)cc2)cc1
Show InChI InChI=1S/C23H28O4/c1-22(2,3)20(24)26-18-11-7-16(8-12-18)15-17-9-13-19(14-10-17)27-21(25)23(4,5)6/h7-14H,15H2,1-6H3
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MMDB

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n/an/a 460n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against human leukocyte elastase at 10e-7 M

J Med Chem 31: 1052-61 (1988)


BindingDB Entry DOI: 10.7270/Q2PC31DJ
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Ligand-Target Pair