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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50023874   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))
BDBM50023874
PNG
(CHEMBL3325508)
Show SMILES FCCN1CCC(CC1)NC(=O)c1ccc(COc2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C22H24F4N2O2/c23-11-14-28-12-9-19(10-13-28)27-21(29)17-3-1-16(2-4-17)15-30-20-7-5-18(6-8-20)22(24,25)26/h1-8,19H,9-15H2,(H,27,29)
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PC sid
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Similars

Article
PubMed
n/an/a 99n/an/an/an/an/an/a



Toray Industries, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrs


Bioorg Med Chem Lett 24: 4603-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.059
BindingDB Entry DOI: 10.7270/Q2K64KN1
More data for this
Ligand-Target Pair