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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50061820   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dimer of Protein farnesyltransferase subunit beta


(Homo sapiens (Human))
BDBM50061820
PNG
(1-[4-(8-Chloro-3-methylsulfanyl-5,6-dihydro-benzo[...)
Show SMILES [#6]-[#16]-c1cnc2c(-[#6]-[#6]-c3cc(Cl)ccc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6]-c2ccncc2)c1
Show InChI InChI=1S/C27H26ClN3OS/c1-33-23-16-21-3-2-20-15-22(28)4-5-24(20)26(27(21)30-17-23)19-8-12-31(13-9-19)25(32)14-18-6-10-29-11-7-18/h4-7,10-11,15-17H,2-3,8-9,12-14H2,1H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Compound was tested for the inhibition of Farnesyltransferase


J Med Chem 40: 4290-301 (1998)


Article DOI: 10.1021/jm970464g
BindingDB Entry DOI: 10.7270/Q2NC60B2
More data for this
Ligand-Target Pair