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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50081327   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tumor necrosis factor


(Homo sapiens (Human))		BDBM50081327
PNG
(4-(6,7-Dimethoxy-4-oxo-4H-quinazolin-3-yl)-butyric...)
Show SMILES CCOC(=O)CCCn1cnc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C16H20N2O5/c1-4-23-15(19)6-5-7-18-10-17-12-9-14(22-3)13(21-2)8-11(12)16(18)20/h8-10H,4-7H2,1-3H3
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PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
The compound was tested in vitro for inhibitory activity against Tumor necrosis factor alpha from human PMBC cell line by ELISA test.

J Med Chem 42: 3860-73 (1999)


BindingDB Entry DOI: 10.7270/Q2TH8NDH
More data for this
Ligand-Target Pair