Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50093005 ((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against Leucyl-tRNA synthetase from staphylococcus aureus WCUH29 | Bioorg Med Chem Lett 10: 2263-6 (2001) BindingDB Entry DOI: 10.7270/Q2PN94W3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoleucyl-tRNA synthetase (Rattus norvegicus) | BDBM50093005 ((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...) | UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liver | Bioorg Med Chem Lett 10: 2263-6 (2001) BindingDB Entry DOI: 10.7270/Q2PN94W3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Valine--tRNA ligase (Homo sapiens (Human)) | BDBM50093005 ((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against VRS (valyl tRNA synthetase) from staphylococcus aureus WCUH29 | Bioorg Med Chem Lett 10: 2263-6 (2001) BindingDB Entry DOI: 10.7270/Q2PN94W3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoleucine--tRNA ligase (Staphylococcus aureus) | BDBM50093005 ((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29 | Bioorg Med Chem Lett 10: 2263-6 (2001) BindingDB Entry DOI: 10.7270/Q2PN94W3 | |||||||||||
More data for this Ligand-Target Pair |