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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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Compile Data Set for Download or QSAR
Found
3
hits of ic50 for monomerid = 50130224
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human))
BDBM50130224
(6,8-Dichloro-7-methoxy-9H-beta-carboline | CHEMBL3...)
Show SMILES
COc1c(Cl)cc2c3cc[nH]cc3nc2c1Cl
Show InChI
InChI=1S/C12H8Cl2N2O/c1-17-12-8(13)4-7-6-2-3-15-5-9(6)16-11(7)10(12)14/h2-5,15H,1H3
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
PubMed
n/a
n/a
170
n/a
n/a
n/a
n/a
n/a
n/a
Millennium Pharmaceuticals Inc.
Curated by
ChEMBL
Assay Description
Inhibitory activity against IkappaB kinase(IKK) isolated from HeLa cells activated with recombinant MEEK1 in an ELISA phosphorylaton assay.
Bioorg Med Chem Lett
13:
2419
-
22
(2003)
BindingDB Entry DOI:
10.7270/Q2PK0FJ7
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma
(Homo sapiens (Human))
BDBM50130224
(6,8-Dichloro-7-methoxy-9H-beta-carboline | CHEMBL3...)
Show SMILES
COc1c(Cl)cc2c3cc[nH]cc3nc2c1Cl
Show InChI
InChI=1S/C12H8Cl2N2O/c1-17-12-8(13)4-7-6-2-3-15-5-9(6)16-11(7)10(12)14/h2-5,15H,1H3
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
PubMed
n/a
n/a
>2.50E+4
n/a
n/a
n/a
n/a
n/a
n/a
Millennium Pharmaceuticals Inc.
Curated by
ChEMBL
Assay Description
Inhibitory activity against protein kinase A.
Bioorg Med Chem Lett
13:
2419
-
22
(2003)
BindingDB Entry DOI:
10.7270/Q2PK0FJ7
More data for this
Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139
(Homo sapiens (Human))
BDBM50130224
(6,8-Dichloro-7-methoxy-9H-beta-carboline | CHEMBL3...)
Show SMILES
COc1c(Cl)cc2c3cc[nH]cc3nc2c1Cl
Show InChI
InChI=1S/C12H8Cl2N2O/c1-17-12-8(13)4-7-6-2-3-15-5-9(6)16-11(7)10(12)14/h2-5,15H,1H3
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
PubMed
n/a
n/a
>2.50E+4
n/a
n/a
n/a
n/a
n/a
n/a
Millennium Pharmaceuticals Inc.
Curated by
ChEMBL
Assay Description
Inhibitory activity against protein kinase C.
Bioorg Med Chem Lett
13:
2419
-
22
(2003)
BindingDB Entry DOI:
10.7270/Q2PK0FJ7
More data for this
Ligand-Target Pair
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