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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50130848   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM50130848
PNG
(CHEMBL3634743)
Show SMILES Fc1ccc(cc1)-c1ncc(F)cc1-c1ccc(OCc2ccc3ccccc3n2)cc1
Show InChI InChI=1S/C27H18F2N2O/c28-21-10-5-20(6-11-21)27-25(15-22(29)16-30-27)18-8-13-24(14-9-18)32-17-23-12-7-19-3-1-2-4-26(19)31-23/h1-16H,17H2
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n/an/a 194n/an/an/an/an/an/a



Glenmark Research Centre

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...

J Med Chem 58: 8292-308 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01240
BindingDB Entry DOI: 10.7270/Q2833TVD
More data for this
Ligand-Target Pair