BindingDB PrimarySearch

Found 6 hits of ic50 for monomerid = 50132679
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50132679 (CHEMBL111128 \| Methyl-((2S,3S)-3-naphthalen-2-yl-b...) Show SMILES CNC[C@H]1C2CCC(C2)[C@@H]1c1ccc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Curated by ChEMBL					Assay Description In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosome				Bioorg Med Chem Lett 13: 3277-80 (2003) BindingDB Entry DOI: 10.7270/Q29W0DXF
Lilly Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50132679 (CHEMBL111128 \| Methyl-((2S,3S)-3-naphthalen-2-yl-b...) Show SMILES CNC[C@H]1C2CCC(C2)[C@@H]1c1ccc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL					Assay Description Inhibition of SERT (unknown origin) assessed as reduction of [3H]5-HT re-uptake				J Med Chem 61: 2133-2165 (2018) Article DOI: 10.1021/acs.jmedchem.6b01827 BindingDB Entry DOI: 10.7270/Q2BV7K8M
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50132679 (CHEMBL111128 \| Methyl-((2S,3S)-3-naphthalen-2-yl-b...) Show SMILES CNC[C@H]1C2CCC(C2)[C@@H]1c1ccc2ccccc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL					Assay Description Inhibition of NET (unknown origin) assessed as reduction of [3H]-NE re-uptake				J Med Chem 61: 2133-2165 (2018) Article DOI: 10.1021/acs.jmedchem.6b01827 BindingDB Entry DOI: 10.7270/Q2BV7K8M
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50132679 (CHEMBL111128 \| Methyl-((2S,3S)-3-naphthalen-2-yl-b...) Show SMILES CNC[C@H]1C2CCC(C2)[C@@H]1c1ccc2ccccc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-NE re-uptake into synaptosome				Bioorg Med Chem Lett 13: 3277-80 (2003) BindingDB Entry DOI: 10.7270/Q29W0DXF
Lilly Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50132679 (CHEMBL111128 \| Methyl-((2S,3S)-3-naphthalen-2-yl-b...) Show SMILES CNC[C@H]1C2CCC(C2)[C@@H]1c1ccc2ccccc2c1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Curated by ChEMBL					Assay Description Displacement of [3H]-Nisoxetine from norepinephrin transpoter				Bioorg Med Chem Lett 13: 3277-80 (2003) BindingDB Entry DOI: 10.7270/Q29W0DXF
Lilly Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50132679 (CHEMBL111128 \| Methyl-((2S,3S)-3-naphthalen-2-yl-b...) Show SMILES CNC[C@H]1C2CCC(C2)[C@@H]1c1ccc2ccccc2c1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL					Assay Description Inhibition of DAT (unknown origin) assessed as reduction of [3H]-DA re-uptake				J Med Chem 61: 2133-2165 (2018) Article DOI: 10.1021/acs.jmedchem.6b01827 BindingDB Entry DOI: 10.7270/Q2BV7K8M
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL					More data for this Ligand-Target Pair