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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50151183   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50151183
PNG
(5-(4-Benzyl-piperazin-1-yl)-2-furan-2-yl-[1,2,4]tr...)
Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H20N8O/c20-17-22-18(23-19-21-16(24-27(17)19)15-7-4-12-28-15)26-10-8-25(9-11-26)13-14-5-2-1-3-6-14/h1-7,12H,8-11,13H2,(H2,20,21,22,23,24)
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Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Universita di Trieste

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase act...

J Med Chem 54: (2011)


Article DOI: 10.1021/jm101349u
BindingDB Entry DOI: 10.7270/Q2445MXP
More data for this
Ligand-Target Pair