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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50166918   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM50166918
PNG
(CHEMBL3798090)
Show SMILES Cn1c(cc2c(ncnc12)-c1ccc(NC(=O)C(C)(C)C)cc1)C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H26N4O3/c1-26(2,3)25(32)29-19-12-10-18(11-13-19)22-20-14-21(30(4)23(20)28-16-27-22)24(31)33-15-17-8-6-5-7-9-17/h5-14,16H,15H2,1-4H3,(H,29,32)
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Article
PubMed
n/an/a 786n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged JAK2 expressed in baculovirus expression system using Z'-LYTE Try6 peptide as substrate incubated for 1 hr...

Bioorg Med Chem Lett 26: 2936-2941 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.027
BindingDB Entry DOI: 10.7270/Q2GB25ZS
More data for this
Ligand-Target Pair