Found 6 hits of ic50 for monomerid = 50197710 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50197710
(CHEMBL3959997)Show SMILES Cc1cc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N Show InChI InChI=1S/C21H17N5O/c1-12-8-14-9-15(6-7-18(14)24-12)26-21(22)16(11-23-26)20(27)19-10-13-4-2-3-5-17(13)25-19/h2-11,24-25H,22H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assay |
J Med Chem 59: 10586-10600 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Homo sapiens (Human)) | BDBM50197710
(CHEMBL3959997)Show SMILES Cc1cc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N Show InChI InChI=1S/C21H17N5O/c1-12-8-14-9-15(6-7-18(14)24-12)26-21(22)16(11-23-26)20(27)19-10-13-4-2-3-5-17(13)25-19/h2-11,24-25H,22H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assay |
J Med Chem 59: 10586-10600 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50197710
(CHEMBL3959997)Show SMILES Cc1cc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N Show InChI InChI=1S/C21H17N5O/c1-12-8-14-9-15(6-7-18(14)24-12)26-21(22)16(11-23-26)20(27)19-10-13-4-2-3-5-17(13)25-19/h2-11,24-25H,22H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assay |
J Med Chem 59: 10586-10600 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50197710
(CHEMBL3959997)Show SMILES Cc1cc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N Show InChI InChI=1S/C21H17N5O/c1-12-8-14-9-15(6-7-18(14)24-12)26-21(22)16(11-23-26)20(27)19-10-13-4-2-3-5-17(13)25-19/h2-11,24-25H,22H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assay |
J Med Chem 59: 10586-10600 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 4
(Homo sapiens (Human)) | BDBM50197710
(CHEMBL3959997)Show SMILES Cc1cc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N Show InChI InChI=1S/C21H17N5O/c1-12-8-14-9-15(6-7-18(14)24-12)26-21(22)16(11-23-26)20(27)19-10-13-4-2-3-5-17(13)25-19/h2-11,24-25H,22H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human FGFR4 by time-resolved fluorescence or time-resolved fluorescence assay |
J Med Chem 59: 10586-10600 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50197710
(CHEMBL3959997)Show SMILES Cc1cc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N Show InChI InChI=1S/C21H17N5O/c1-12-8-14-9-15(6-7-18(14)24-12)26-21(22)16(11-23-26)20(27)19-10-13-4-2-3-5-17(13)25-19/h2-11,24-25H,22H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assay |
J Med Chem 59: 10586-10600 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV |
More data for this
Ligand-Target Pair | |
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